Melanotan II typical research dosing
Across the available literature, Melanotan II is most commonly administered at 250–1000 mcg per dose, 1 time(s) per day, via subcutaneous injection. Research protocols typically use 250–1000 mcg subcutaneously. Most protocols start at 250 mcg to assess tolerance before escalating. MT-II is not used daily continuously; most research cycles are 4–6 weeks. Not for use without UV exposure for melanin production goals — some sun or UV exposure is required for melanin deposition.
Melanotan II unit-conversion table
The number of insulin-syringe units you draw depends on how much bacteriostatic water you used to reconstitute the vial. The table below shows units to draw on a U-100 syringe for a 10 mg Melanotan II vial at common reconstitution volumes.
| Diluent (mL) | Concentration | 250 mcg | 625 mcg | 1000 mcg |
|---|---|---|---|---|
| 1 mL | 10000 mcg/mL | 2.5 units | 6.3 units | 10.0 units |
| 2 mL | 5000 mcg/mL | 5.0 units | 12.5 units | 20.0 units |
| 3 mL | 3333 mcg/mL | 7.5 units | 18.8 units | 30.0 units |
| 5 mL | 2000 mcg/mL | 12.5 units | 31.3 units | 50.0 units |
Melanotan II cycle length
Most reported Melanotan II protocols run 4 weeks on, then 4 weeks off. Cycles are used in research to study washout, receptor sensitivity, and to re-baseline endogenous signaling before re-introducing the compound.
Melanotan II half-life and timing
Melanotan II has a half-life of approximately 30 hours. This influences dose frequency: shorter half-lives often require multiple doses per day to maintain steady-state levels, while longer half-lives can be dosed less frequently.